Stephania Tetrandra Extract Tetrandrine

Stephania Tetrandra Extract Tetrandrine – Premium Botanical Active for Antisepsis & Anti-Inflammation

Easy Health Inc. supplies pharmaceutical grade Stephania Tetrandra Extract Tetrandrine with a purity confirmed ≥98% by HPLC, obtained from verified Stephania tetrandra S. Moore roots. Our solubilized white powder formulation provides higher bioavailability and fast skin penetration overcoming major hurdles in cosmeceutical and pharmaceutical applications. ISO/Halal/Kosher certification, +11 years professional botanical extract experience, 0 aristolochic acid pollution, steady supply with full batch traceability. Our water soluble version eliminates worries about organic solvents and may be easily added to serums, lotions and anti-inflammatory compositions. Typical concentration is in the range 0.05% to 0.5% and is appropriate to applications on sensitive skin.

What Is Stephania Tetrandra Extract Tetrandrine?

It is a high purity bisbenzylisoquinoline alkaloid derived from the dried roots of Stephania tetrandra S. Moore, a traditional medicinal herb. It is the main active component of Radix Stephaniae Tetrandrae, and acts as a strong blocker of L-type calcium channels.

This pharmaceutical grade extract addresses three key pain areas in the industry. First, it removes the potential of nephrotoxicity, by guaranteeing complete freedom from aristolochic acid contamination, a major safety worry with look-alike species. Second, our standardised quantification of alkaloids by HPLC ensures the alkaloid concentration is constant between batches. Third, it offers a natural choice for treating chronic inflammatory and fibrotic diseases with less toxicity than synthetic choices.

The perfect ingredient for formulations designed for safe and effective antisepsis and anti-inflammation oriented applications.

Product Specifications

Key Technical Properties

Our product features the molecular formula C₃₈H₄₂N₂O₆ with a molecular weight of 622.75 g/mol. You will have a white to off-white crystalline powder in its refined state, melting point 217°C to 219°C.

The extract is remarkably stable in terms of thermal stability throughout pharmaceutical processing and retains structural integrity with high-shear mixing and UV exposure. Our solubilized formulation resolves the classical poor water solubility problem and is therefore well suited for water based cosmetic and medicinal applications.

Quality requirements for pharmaceutical uses require purity of ≥98% by HPLC. We maintain tight limits on heavy metals (<10ppm) and residual solvents per USP/EP requirements. It possesses pharmacological capabilities of multiple targets, such as T-type and L-type calcium channel inhibition, which may be related to its anti-inflammatory effect.

Core Advantages for Your Formulations

Improved Absorption of Standard Tetrandrine: Faster Skin Penetration and Better Absorption of Our Water-Soluble Formulation. You get benefits sooner and you need to take less of it.

Strong Anti-inflammatory Action: Effectively inhibits pathways of NF-κB and pro-inflammatory cytokines. This is good for soothing sensitive and irritated skin in cosmeceutical applications that require anti-sepsis and anti-inflammation properties.

Anti-Aging & Repair Properties: Reduces UV-induced collagen degradation and helps restore the skin matrix. You may design solutions that offer tighter, younger looking skin, while managing chronic inflammatory disorders.

Clean & Stable Formulation: The solubilized form eliminates problems related to organic solvents and is straightforward to incorporate into water-based formulations. You will have a simpler and cheaper production procedure.

Applications Across Industries

You can deploy Stephania Tetrandra Extract Tetrandrine across three primary sectors requiring high-performance botanical actives.

Pharmaceutical Manufacturing – Used as a core API in anti-hypertensive and anti-arrhythmic medications. It's particularly valuable in clinical environments where multi-drug resistance reversal is needed.

Pulmonary Health Research – Specifically utilized in therapeutic protocols for silicosis and pulmonary fibrosis. Its ability to inhibit collagen synthesis addresses critical treatment challenges in respiratory conditions.

Specialized Cosmeceuticals – Integrated into advanced topical formulations for chronic skin conditions like psoriasis or severe acne. The extract maintains structural integrity even when exposed to demanding manufacturing conditions, making it suitable for professional skincare lines focused on antisepsis and anti-inflammation.

Quality Control Standards

We have a strict quality control system for the product with five necessary inspection factors.

3. Authenticity and Purity HPLC fingerprinting helps identify Tetrandrine from Fangchinoline with a purity threshold of 98% or above Same quality in every batch.

Safety Screening – Mandatory LC-MS/MS testing for Aristolochic Acid I & II confirms 'non-detectable' status. This is critical for your foreign regulatory compliance with FDA/EMA.

Heavy Metal Analysis – Inductively Coupled Plasma Mass Spectrometry Lead, Arsenic, Cadmium and Mercury levels. Your formulas adhere to the highest safety standards.

Physical Characterisation – Particle size distribution (D50/D90), tapping density analysis for uniform mixing in solid dosage form. This means your line of production reaps the rewards of manufacturing efficiency.

Microbiological Control – Total aerobic microbial count and yeast/mold count testing follows USP <61> and <62>. You can trust the microbiological safety of every lot.

FAQ

Q: What is the recommended usage rate in formulations?

A: Typical concentration is 0.05%–0.5% in serums and creams. Start low for sensitive skin applications; always perform patch testing before full-scale production.

Q: Is this extract suitable for water-based formulations?

A: Yes. Our solubilized version is specifically designed for easy incorporation into water-based cosmetic and pharmaceutical formulations, eliminating traditional solubility challenges.

Q: How do you ensure there's no aristolochic acid contamination?

A: We perform compulsory LC-MS/MS testing on every batch to ensure aristolochic acid I & II remain at 'non-detectable' levels, meeting FDA and EMA safety requirements.

Q: What certifications does your facility hold?

A: Our production facility is certified with ISO, Halal, Kosher, FDA Registration, USDA NOP & EU Organic, and HACCP, ensuring compliance with global market requirements.

Q: What is your typical lead time for orders?

A: Standard products ship immediately from ready stock. Customized formulations typically require 3–5 days lead time, ensuring efficient supply chain support.

Contact Us

Ready to enhance your formulations with premium Stephania Tetrandra Extract Tetrandrine? Contact us today at devin@easyhealthbio.com for samples, technical specifications, and custom solutions tailored to your needs.