Easy Health Inc. provides Sophora Flavescens Root Extract ≥98% Matrine purity for use in pharmaceuticals, cosmeceuticals and nutraceuticals. Our extract is rigorously tested by HPLC and is thermally stable up to 80°C with optimal pH compatibility (4.0–7.0). With more than 11 years of experience in botanical extraction, and with our ISO, Halal, Kosher and USDA Organic certifications, we are able to provide batch-to-batch consistency, and full traceability from raw material procurement to final delivery. You can be certain of your formulation demands as each manufacturing cycle is compliant to international heavy metal restrictions (Pb ≤2ppm, As ≤1ppm) and microbiological safety regulations.
This extract is a concentrated source of quinolizidine alkaloids, mainly Matrine and Oxymatrine, and bioactive flavonoids obtained from the dried roots of Sophora flavescens Aiton (common name Ku Shen or Bitter Sophora).
It deals with important industry difficulties in current applications: the growing need for clean-label ingredients, the necessity for efficient non-steroidal anti-inflammatory drugs in cosmeceuticals and the management of microbial resistance in topical formulations. Our innovative procedures of extraction and purification of Ethanol give a pure white crystalline powder which has demonstrated efficacy.
This botanical solution provides you with a natural alternative to synthetic antimicrobials. It enhances your differentiation in competitive marketplaces and meets regulatory standards globally.

| Parameter | Specification |
|---|---|
| Product Name | Sophora Flavescens Root Extract |
| Botanical Source | Sophora flavescens Aiton. |
| Other Name | Bitter Sophora Root Extract / Sophora Flavescens Extract |
| Main Ingredient | Matrine |
| CAS No. | 519-02-8 |
| Molecular Formula | C₁₅H₂₄N₂O |
| Molecular Weight | 248.36 |
| Appearance | White crystalline powder |
| Purity | ≥98% |
| Test Method | HPLC |
| Loss on Drying | ≤5.0% |
| Residue on Ignition | ≤0.5% |
| Heavy Metals (as Pb) | ≤10 ppm |
| Lead (Pb) | ≤2 ppm |
| Arsenic (As) | ≤1 ppm |
| Cadmium (Cd) | ≤1 ppm |
| Mercury (Hg) | ≤0.1 ppm |
| Total Plate Count | ≤1000 CFU/g |
| Yeast & Mold | ≤100 CFU/g |
| E. Coli | Negative |
| Salmonella | Negative/25g |

Strong Anti-Inflammatory Effects
Matrine has an efficient inhibition on pro-inflammatory cytokines in vitro. This makes it great for treating acne, eczema and irritable skin disorders without the adverse effects of synthetic steroids.
Broad Spectrum Antimicrobial Protection
The extract showed excellent bacteriostatic and antifungal action against Staphylococcus aureus, Candida and acne-causing microorganisms. You don’t have to worry about creating antibiotic resistance and you can count on its antibacterial potency.
Natural Skin Lightening
This extract inhibits melanin formation and tyrosinase activity to give safe and efficient brightening for hyperpigmentation concerns. It is ideal for your clean beauty and cosmeceutical product lines.
Multi-Target Anti-Aging Properties
It's antioxidant and anti-proliferative properties aid to minimise UV damage, encourage skin renewal and preserve healthy barrier function. Your customers will love seeing outcomes backed by botanical science.

Advanced Cosmeceuticals for Oily Skin and Acne
Sophora Flavescens Root Extract is a wonderful addition to clinical skincare formulas to suppress Propionibacterium acnes and regulate activity of the sebaceous glands. It supports skin barrier integrity while providing demonstrable anti-acne benefits.
Therapeutic Scalp Care Solutions
Its capacity to kerb Malassezia furfur growth and lessen scalp erythema proves useful in professional hair care products.
It has a better long term safety profile than many synthetic anti-dandruff treatments giving you a competitive edge.
Health Supplements in Clean Label
This standardised extract is useful for nutraceutical applications for liver health and immunological modulation. It is high purity and quality controlled strictly, fit for pharmaceutical grade needs in capsule and tablet manufacturing.

All the batches are subject to quality control standards developed for industrial reliability:
Active Ingredient Assay: High Performance Liquid Chromatography (HPLC) accurately determines the amount of Matrine and Oxymatrine
Heavy Metal Screening: Inductively Coupled Plasma Mass Spectrometry (ICP-MS) verifies all heavy metals are well below international limits.
Pesticide Residue Analysis: GC-MS/LC-MS testing for more than 200 banned compounds to meet the standards of international markets, such as EC 396/2005.
Microbial Safety: Total plate count is below 1000 CFU/g, with proven absence of pathogens including E. coli and Staphylococcus aureus.
Solvent Residue Monitoring: Headspace GC to verify conformance to pharmacopoeia limits for residual ethanol.
Our ISO, Halal, Kosher and USDA Organic certifications offer further assurance. Full batch traceability means you can verify quality from source to delivery.

We have over 11 years of experience in botanical extraction and we bring together technical innovation and a customer-first approach. Our R&D staff is available for formula optimisation, application advice and technological troubleshooting.
We provide flexible OEM/ODM service including custom specs, packaging design and labelling. Standard products ship out from ready stock right away and customised orders are often delivered within 3–5 days.
Our global logistics network is efficient and works with FedEx, DHL and UPS. We find the best shipping solutions for your product type, destination and budget needs.
You can count on us for reliable quality, fair price, and timely technical support. We believe in long-term collaborations that enable both of us to flourish together.

Q: What is the recommended usage rate in formulations?
A: Typical concentration ranges from 0.5% to 2.0% in creams and serums. Always perform patch testing before full-scale production due to its potent alkaloid nature.
Q: Is this extract suitable for sensitive skin formulations?
A: Yes, when used at recommended concentrations. Its anti-inflammatory properties actually benefit sensitive skin, though initial compatibility testing is essential.
Q: What certifications do you provide with each shipment?
A: We provide Certificate of Analysis (CoA), MSDS, and relevant certifications including ISO, Halal, Kosher, and Organic certificates upon request.
Q: Can you customize the purity level?
A: Absolutely. While our standard specification is ≥98% Matrine, we offer customized concentrations from 1% for cosmetic applications to pharmaceutical grades.

Ready to enhance your formulations with premium Sophora Flavescens Root Extract? Contact us at devin@easyhealthbio.com for samples, technical specifications, or custom solutions tailored to your needs.
