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Berberine 97 Hcl

Product Name:Berberine 97 Hcl
Botanical Source:Cortex Phellodendri Chinensis
Part Used: Rhizome (root)
CAS No:. (Berberine HCl) 633-65-8
Molecular Formula: C₂₀H₁₈ClNO₄
Molecular Weight: 371.81 g/mol
Active Compounds: Berberine, Coptisine, Jatrorrhizine, Palmatine, Epiberberine
Appearance:Yellow powder
Assay:Min97%
Test Method:Titration/HPLC
Product Description

Premium Berberine 97 Hcl – Ultra-High Purity Natural Extract for Animal Nutrition

Easy Health Inc. proudly presents our pharmaceutical-grade Berberine 97 Hcl, a high-potency natural extract standardized to ≥97% purity via HPLC analysis. This yellow crystalline powder is extracted from superior Cortex Phellodendri Chinensis rhizomes and guarantees consistent efficacy for cattle, poultry and aquaculture applications. We have more than 11 years of manufacturing experience and are fully certified with ISO/HACCP/HALAL/KOSHER. We maintain strict quality control, including heavy metal restrictions (Lead ≤3.0 mg/kg, Arsenic ≤2.0 mg/kg) and microbiological safety (Total Plate Count ≤1,000 cfu/g). We have a sophisticated extraction process that ensures no risk of antibiotic resistance, making it the product of choice for antibiotic-free feed programmes where precision, safety and measurable results are required.

Berberine

What Makes Our Berberine 97 Hcl Stand Out?

Our product is the standard in botanical feed additives. Some are lower grade extracts and can vary in potency. We keep ours consistent at pharmaceutical grade and verify it using HPLC.

Each batch is purified in several steps to remove interfering alkaloids such as Palmatine and Jatrorrhizine. This helps guarantee your formulations provide consistent antibacterial performance and gut health advantages with each production cycle.

You have a stable, free flowing powder that blends well into premixes, concentrates and full feeds. The hydrochloride salt version has better water solubility than berberine sulphate and hence improves absorption in the gut.

Cortex Phellodendri contains an extensive alkaloid profile including Coptisine, Epiberberine, etc. for broad spectrum efficacy. It is a molecule with molecular weight 371.81 g/mol and CAS No. 633-65-8 which is in accordance with international pharmacopoeia standards.

Berberine advantage

Technical Specifications

Parameter Specification
Product Name Berberine 97 Hcl
Botanical Source Cortex Phellodendri Chinensis
Part Used Rhizome (root)
CAS No. 633-65-8
Molecular Formula C₂₀H₁₈ClNO₄
Molecular Weight 371.81 g/mol
Active Compounds Berberine, Coptisine, Jatrorrhizine, Palmatine, Epiberberine
Appearance Yellow powder
Assay Min 97%
Test Method Titration/HPLC
Loss on Drying ≤ 5.0%
Ash Content ≤ 5.0%
Moisture ≤ 7.0%
Lead (Pb) ≤ 2.0–3.0 mg/kg
Arsenic (As) ≤ 2.0 mg/kg
Cadmium (Cd) ≤ 1.0–2.0 mg/kg
Mercury (Hg) ≤ 1.0 mg/kg
Pesticide Residues ≤ 1.0 mg/kg
Residual Solvents (Ethanol) ≤ 50 ppm
Total Plate Count ≤ 1,000 cfu/g
Yeast & Molds ≤ 100 cfu/g
Coliforms < 3.0 MPN/g
E. coli Negative (in 10g)
Salmonella Negative (in 25g)
Staphylococcus aureus Negative (in 10g)

Berberine Packing

Five Core Advantages for Feed Manufacturers

1. Ultra High Purity (≥97%)

Every batch is of highest potency and exact dose. Our standardised extraction removes the guesswork so you can formulate with confidence. Pharmaceutical grade purity assures the animal response will be predictable and the ingredients will not vary.

2. Broad-Spectrum Antimicrobial Action

Our medicine is active against Gram-positive and Gram-negative bacteria, fungus and protozoa without generating resistance. This is suitable for your antibiotic-free manufacturing processes, meeting the regulatory pressures and the consumer needs.

3. Better Gut Health Support

You will observe less intestinal inflammation and preservation of mucosal barrier integrity. The chemical modifies microbial balance naturally, reducing diarrhoea rates in young animals and enhancing overall herd health.

4. Proven Growth Performance

Better feed conversion ratios and daily weight gains for your animals. More efficient nutrient absorption means more profitable poultry, swine and ruminant businesses.

5. Natural & Safe Image

It is a plant-based component with low toxicity and does not accumulate in tissues. You easily meet export regulations, promoting sustainable animal production, all in complete compliance with international norms.

Berberine R&D

Recommended Applications & Dosage

Poultry Production: 

Add 50-200g per tonne of finished feed to minimise necrotic enteritis and coccidiosis pressure. You will see enhanced feed efficiency and uniform flock performance.

Swine Nutrition:

Add 100 to 300 g/ton for weanling and developing piglets. It improves gut development throughout the critical transition stages and decreases diarrhoea post-weaning.

Feeding Ruminants:

Dairy and beef diets. 50–150 g per tonne. The substance helps to maintain rumen health and supports the metabolic balance in periods of strong performance.

Aquaculture Systems:

Dose 50–200 g per tonne of aquafeed for better water quality and disease resistance. You have natural pathogen control with no environmental issues.

Always make trial batches to identify the best inclusion rates for your own production conditions.

Berberine application

Quality You Can Trace & Trust

Our Berberine 97 Hcl is supplied with full batch documentation per kg. You get COA (Certificate of analysis) with HPLC chromatograms, heavy metal screening by ICP-MS, microbiological testing findings.

Our facility is ISO 9001 and ISO 22000 accredited and follows stringent GMP regulations. Raw materials are identity-verified before processing by botanical authentication and alkaloid fingerprinting.

Residual solvent analysis is performed by Gas Chromatography to validate ethanol levels below 50 ppm. Our extraction technique never uses methanol or any hazardous Class 1 solvents.

Pesticide residues remain below the 1.0 mg/kg limit required by USDA NOP Organic and EU standards, as confirmed by third-party testing. We are an FDA-registered facility to help you satisfy regulations for international trade and save delays from extra testing.

We can provide audit-ready documentation with full traceability from the harvest place to the shipping container. This visibility preserves your brand image and passes the most rigors supply chain audits.

Berberine Certification

Packaging & Global Logistics

We provide flexible packing solutions, depending on your order volume. Standard packaging is fibre drums with double-lined food-grade polythene bags (25kg net).

We may offer multi-layer kraft paper bags or bespoke packaging with your logo for bulk orders. FDA food contact acceptable for all materials.

For urgent orders, our logistics staff arranges air freight through FedEx, DHL and UPS. Large volume shipments to any port in the world at cost effective sea freight rates.

Standard specifications are available for rapid despatch. Custom orders usually ship 3-5 business days following confirmation.

Temperature controlled shipping to maintain product stability in transit. You receive tracking information and customs documentation support for seamless passage at destination

Berberine Bulk Goods

FAQ

Q: Where does this product come from?

A: Obtained from dried rhizomes of Coptis chinensis Franch. (Chinese Goldthread) growing wild in Sichuan, Yunnan and Hubei regions in China.

Q: What is the active ingrediant?

A: Berberine hydrochloride (Berberine HCl), ≥97.0% (HPLC).

Q: How does it look?

A: Fine crystalline powder, yellow to brownish yellow, pronounced harsh flavour.

Q: What is the suggested dose?

A: 50–300 g/ton of finished feed depending on species. Poultry 50–200 g/ton; Swine 100–300 g/ton; Ruminants 50–150 g/ton.

Q: Does it cause bacterial resistance?

A: No. Berberine does not cause bacterial resistance, as compared to conventional antibiotics, making it perfect for antibiotic-free production systems.

Q: Are there tissue residues?

A: No. Berberine is metabolized and excreted rapidly with no harmful residues in meat, eggs, or milk.

Q: What is the shelf life?

A: 24 months in original, sealed packaging stored cool, dry, and dark.

Q: What certifications are available?

A: ISO 9001, ISO 22000, HACCP, FSSC 22000, HALAL, KOSHER, and FDA. COA provided per batch.

Q: Is it suitable for aquaculture?

A: Yes. Dosage: 50–200 g/ton of feed for antibacterial and disease resistance support.

Q: How should it be stored after opening?

A: Reseal tightly immediately. Protect from moisture, heat, and light—product is photosensitive.

Berberine Shipment

Partner With Easy Health Inc. Today

Ready to upgrade your feed formulations with pharmaceutical-grade Berberine 97 Hcl? Contact us at devin@easyhealthbio.com for samples, quotations, and expert guidance!